Exercise Moderate Interval as an Alternative Exercise Model to Improve Insulin Sensitivity in Type 2 Diabetes Mellitus

Background: Previous study had found that adherence of patient Diabetes type-2 in moderate to vigorous continuous exercise was poor. Meanwhile regularly needs control fasting plasma glucose T2DM. Exercise interval (EMI) shows a significant effect reduce insulin resistance metabolic syndrome patients. But, studies find the EMI or EMC muscle receptor distribution are still limited. So, purpose this is compare effects vs increasing receptors and reducing T2DM rat models. Methods: An experimental conducted According treatments, rats were randomly assigned into following 3 groups: sedentary group (SG), (EMC) (EMI). Each training session performed on treadmill for eight weeks, three times weekly. Insulin assessed by immunohistochemistry. Meanwhile, determined Homeostatic Model Assessment (HOMA-IR) score measured before after completing session. Results: This = 184% EMC= 158%. Both treatment groups difference (p=0.002), but there no between (p=0.222). HOMA-IR 16.6±4.0 significantly different with such as 43.3±8.6 (p=0.000). There negative correlation (p=0.047, r =-0.520). Conclusion: could increase skeletal muscle, showed better improve sensitivity weeks' exercise. We suggested an alternative Type 2 Mellitus.